CINCINNATI (AP) -- Chris Heisey scored from first base on Todd Frazier's double into the left-field corner as the Cincinnati Reds came from behind for a 4-3 win over the Milwaukee Brewers in 10 innings on Sunday.
Heisey drew a two-out, four-pitch walk from Tyler Thornburgh (3-1), and Frazier followed with a line drive that one-hopped the wall. Heisey beat shortstop Jean Segura's off-target relay to the plate to give the Reds three wins in their four-game series against the team that has the majors' best record at 21-11.
Brandon Phillips greeted reliever Brandon Kintzler with a game-tying 425-foot blast to center with one out in the eighth inning. The homer was Phillips' second of the season and first since April 5.
Sam LeCure (1-1) pitched the 10th for the win.
Brewers starter Kyle Lohse allowed a season-high eight hits, including Brayan Pena's home run, but the right-hander still managed keep the Reds at bay. Lohse lasted 6 1-3 innings, giving up two runs with one walk and two strikeouts.
Cincinnati starter Alfredo Simon, who hadn't allowed more than two runs in any of his first five starts, gave up three in seven innings, along with five hits and one walk with no strikeouts.
Before 32,953 fans - the third straight crowd of at least 32,000 - Scooter Gennett hit Simon's third pitch of the game 357 feet into the right-field seats for his second homer of the season, giving Milwaukee a 1-0 lead. The Brewers made it 2-0 in the third on Carlos Gomez's one-out double to the warning track in left-center and Jonathan Lucroy's two-out single.
Pena hit the first pitch of the third inning 456 feet over the right field wall for his third homer of the season, all in the last five days.
Khris Davis restored the two-run lead with a solo homer to right in the fourth, his fourth of the season.
The Reds again made it a one-run game in the fourth on Frazier's sacrifice fly after Phillips led off with a double - his fourth hit in five at-bats since getting Friday off - and advanced to third on Heisey's groundout.
NOTES: Davis has 15 home runs in his brief two-year career, with five of them against the Reds. ... RF Jay Bruce was scratched from Cincinnati's original starting lineup with left knee soreness. Heisey replaced Bruce in right field and the fourth spot in the batting order. ... Manager Bryan Price expects LHP Aroldis Chapman to be activated for the Reds' homestand that is scheduled to start next Friday. The projected closer is due to take Sunday and Monday off before starting and pitching an inning for Triple-A Louisville on Tuesday, followed by an inning of relief on Wednesday. Chapman is coming back from surgery to repair injuries to his left eye suffered when he was struck by a line drive during a spring training game on March 19.